Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors

Genome-wide epigenetic profiling of breast cancer tumors treated with aromatase inhibitors

Aromatase inhibitors (AI) are extensively used in the treatment of estrogen receptor-positive breast cancers, however resistance to AI treatment is commonly observed. Apart from Estrogen receptor (ERα) expression, no predictive biomarkers for response to AI treatment are clinically applied. Yet, sin...

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Bibliographic Details
Main Authors: Ekaterina Nevedomskaya, Lodewyk Wessels, Wilbert Zwart
Format: Article
Language:English
Published: Elsevier 2014-12-01
Series:Genomics Data
Subjects:
Breast cancer
ChIP-seq
Epigenetic modifications
Aromatase inhibitor treatment outcome
Estrogen Receptor
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596014000567

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http://www.sciencedirect.com/science/article/pii/S2213596014000567

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