E2F6/KDM5C promotes SF3A3 expression and bladder cancer progression through a specific hypomethylated DNA promoter

E2F6/KDM5C promotes SF3A3 expression and bladder cancer progression through a specific hypomethylated DNA promoter

Abstract Background Abnormal expression of splicing factor 3A subunit 3 (SF3A3), a component of the spliceosome, has been confirmed to be related to the occurrence and development of various cancers. However, the expression and function of SF3A3 in bladder cancer (BC) remains unclear. Methods The SF...

Full description

Bibliographic Details
Main Authors: Kai-Long Liu, Yue-Wei Yin, Bao-Sai Lu, Ya-Lin Niu, Dan-Dan Wang, Bei Shi, Hong Zhang, Ping-Ying Guo, Zhan Yang, Wei Li
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Cancer Cell International
Subjects:
SF3A3
KDM5C
Hypomethylation
Proliferation
Bladder cancer
Online Access:https://doi.org/10.1186/s12935-022-02475-4

Internet

https://doi.org/10.1186/s12935-022-02475-4

Similar Items