Melatonin inhibits Japanese encephalitis virus replication and neurotoxicity via calcineurin-autophagy pathways

Melatonin inhibits Japanese encephalitis virus replication and neurotoxicity via calcineurin-autophagy pathways

Abstract Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that has no specific treatment except for supportive medical care. JEV is a neurotropic virus that affects the nervous system and triggers inflammation in the brain. Methods Melatonin is used as a sleep-inducing age...

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Bibliographic Details
Main Authors: Ji-Hong Moon, Jeong-Min Hong, Jae-Won Seol, Byung-Yong Park, Seong Kug Eo, Sang-Youel Park
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Neuroscience
Subjects:
Melatonin
Calcineurin
Japanese encephalitis virus
Autophagy
Online Access:https://doi.org/10.1186/s12868-023-00832-1

Internet

https://doi.org/10.1186/s12868-023-00832-1

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