Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors

Spatial relationships in the urothelial and head and neck tumor microenvironment predict response to combination immune checkpoint inhibitors

Abstract Immune checkpoint inhibitors (ICI) can achieve remarkable responses in urothelial cancer (UC), which may depend on tumor microenvironment (TME) characteristics. However, the relationship between the TME, usually characterized by immune cell density, and response to ICI is unclear. Here, we...

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Bibliographic Details
Main Authors: Alberto Gil-Jimenez, Nick van Dijk, Joris L. Vos, Yoni Lubeck, Maurits L. van Montfoort, Dennis Peters, Erik Hooijberg, Annegien Broeks, Charlotte L. Zuur, Bas W. G. van Rhijn, Daniel J. Vis, Michiel S. van der Heijden, Lodewyk F. A. Wessels
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-46450-1

Internet

https://doi.org/10.1038/s41467-024-46450-1

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