Revisiting Old Ionophore Lasalocid as a Novel Inhibitor of Multiple Toxins

The ionophore lasalocid is widely used as a veterinary drug against coccidiosis. We found recently that lasalocid protects cells from two unrelated bacterial toxins, the cytotoxic necrotizing factor-1 (CNF1) from <i>Escherichia. coli</i> and diphtheria toxin. We evaluated lasalocid&#...

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Bibliographic Details
Main Authors: Nassim Mahtal, Yu Wu, Jean-Christophe Cintrat, Julien Barbier, Emmanuel Lemichez, Daniel Gillet
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
Online Access:https://www.mdpi.com/2072-6651/12/1/26