An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas

An epigenetic gene silencing pathway selectively acting on transgenic DNA in the green alga Chlamydomonas

Strong transgene suppression has been observed in Chlamydomonas reinhardtii, but the underlying mechanism is unknown. Here, the authors identify a sirtuin-type histone deacetylase that selectively acts on transgenic DNA to repress gene expression by assembling a repressive chromatin structure compos...

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Bibliographic Details
Main Authors: Juliane Neupert, Sean D. Gallaher, Yinghong Lu, Daniela Strenkert, Na’ama Segal, Rouhollah Barahimipour, Sorel T. Fitz-Gibbon, Michael Schroda, Sabeeha S. Merchant, Ralph Bock
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19983-4

Internet

https://doi.org/10.1038/s41467-020-19983-4

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