Ets1 Promotes the Differentiation of Post-Selected iNKT Cells through Regulation of the Expression of Vα14Jα18 T Cell Receptor and PLZF

The transcription factor Ets1 is essential for the development/differentiation of invariant Natural Killer T (iNKT) cells at multiple stages. However, its mechanisms of action and target genes in iNKT cells are still elusive. Here, we show that Ets1 is required for the optimal expression of the Vα14...

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Bibliographic Details
Main Authors: Ya-Ting Chuang, Wan-Chu Chuang, Chih-Chun Liu, Chia-Wei Liu, Yu-Wen Huang, Huang-Yu Yang, I-Cheng Ho, Tzong-Shyuan Tai
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/22/22/12199