Functions and therapeutic targets of Siglec-mediated infections, inflammations and cancers

Functions and therapeutic targets of Siglec-mediated infections, inflammations and cancers

Siglecs, sialic acid (SA)-binding immunoglobulin (Ig)-like lectins, belong to a family of Ig-like lectins. All Siglecs have at least two domains including an extracellular domain with variable (V) and constant (C)-set immunoglobulin (Ig) regions, and a transmembrane domain. Some of the Siglecs (Sigl...

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Bibliographic Details
Main Authors: Chia-Hsueh Lin, Ying-Chun Yeh, Kuender D. Yang
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Journal of the Formosan Medical Association
Subjects:
Sialic acid (SA)
Sialic acid-binding immunoglobulin-like lectins (Siglecs)
SA-Siglec axis
Src homology 2 tyrosine phosphatases
Target therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0929664619300968

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http://www.sciencedirect.com/science/article/pii/S0929664619300968

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