Identifying intragenic functional modules of genomic variations associated with cancer phenotypes by learning representation of association networks

Abstract Background Genome-wide Association Studies (GWAS) aims to uncover the link between genomic variation and phenotype. They have been actively applied in cancer biology to investigate associations between variations and cancer phenotypes, such as susceptibility to certain types of cancer and p...

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Bibliographic Details
Main Authors: Minsu Kim, Jennifer E. Huffman, Amy Justice, Ian Goethert, Greeshma Agasthya, VA Million Veteran Program, Ioana Danciu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Medical Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12920-022-01298-6