NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble

NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble

Universally conserved factors from NusG family bind at the upstream fork junction of transcription elongation complexes and modulate RNA synthesis in response to translation, processing, and folding of the nascent RNA. Escherichia coli NusG enhances transcription elongation in vitro by a poorly unde...

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Bibliographic Details
Main Authors: Matti Turtola, Georgiy A Belogurov
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-10-01
Series:eLife
Subjects:
transcription factors
transcription elongation
transcriptional pausing
translocation
base analogues
fluorescence
Online Access:https://elifesciences.org/articles/18096

Internet

https://elifesciences.org/articles/18096

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