Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients

Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients

Paroxetine is one of the most potent selective serotonin reuptake inhibitors (SSRIs) approved for treating depression, panic disorder, and obsessive-compulsive disorder. There is evidence linking genetic polymorphisms and nonlinear metabolism to the Paroxetine’s pharmacokinetic (PK) variability. The...

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Bibliographic Details
Main Authors: Xiao-lin Li, Shan-qing Huang, Tao Xiao, Xi-pei Wang, Wan Kong, Shu-jing Liu, Zi Zhang, Ye Yang, Shan-shan Huang, Xiao-jia Ni, Hao-yang Lu, Ming Zhang, Yu-guan Wen, De-wei Shang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
paroxetine
Chinese
dose-dependent
formulation
population pharmacokinetics
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.966622/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.966622/full

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