Granulocyte Colony-Stimulating Factor Ameliorates Endothelial Activation and Thrombotic Diathesis Biomarkers in a Murine Model of Hind Limb Ischemia

Granulocyte Colony-Stimulating Factor Ameliorates Endothelial Activation and Thrombotic Diathesis Biomarkers in a Murine Model of Hind Limb Ischemia

Novel therapies in peripheral arterial disease, such as granulocyte colony-stimulating factor (GCSF) administration, might result in anti-atherosclerotic effects. In this study, we used 10-week-old male ApoE<sup>−/−</sup> mice, which were fed an atherosclerosis-inducing diet for four wee...

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Bibliographic Details
Main Authors: Angeliki Valatsou, Panagiotis Theofilis, Spyridon Simantiris, Georgia Vogiatzi, Alexandros Briasoulis, Marios Sagris, Evangelos Oikonomou, Alexios S. Antonopoulos, Alkistis Pantopoulou, Narjes Nasiri-Ansari, Elizabeth Fragopoulou, Despoina Perrea, Konstantinos Tsioufis, Dimitris Tousoulis
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomedicines
Subjects:
granulocyte colony-stimulating factor
inflammation
endothelium
adhesion molecule
plasminogen activator inhibitor-1
limb ischemia
Online Access:https://www.mdpi.com/2227-9059/10/9/2303

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https://www.mdpi.com/2227-9059/10/9/2303

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