Effects of the combination of Epimedii Folium and Ligustri Lucidi Fructus on apoptosis and autophagy in SOP rats and osteoblasts via PI3K/AKT/mTOR pathway

Effects of the combination of Epimedii Folium and Ligustri Lucidi Fructus on apoptosis and autophagy in SOP rats and osteoblasts via PI3K/AKT/mTOR pathway

Background: This study aimed to investigate the effects of the combination of Epimedii Folium (EF) and Ligustri Lucidi Fructus (LLF) on regulating apoptosis and autophagy in senile osteoporosis (SOP) rats. Methods: Firstly, we identified the components in the decoction and drug-containing serum of E...

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Bibliographic Details
Main Authors: Yuman Li, Ping Yu, Yingying Gao, Zitong Ma, Han Wang, Yuting Long, Zaina Ma, Renhui Liu
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Epimedii Folium / Ligustri Lucidi Fructus
UPLC-Q-TOF-MS
Senile osteoporosis
Osteoblast
Autophagy / apoptosis
PI3K/Akt/mTOR
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224002300

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http://www.sciencedirect.com/science/article/pii/S0753332224002300

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