Case report: Robust response to sintilimab in advanced distal cholangiocarcinoma with PD-L1 expression and DNA damage repair

Case report: Robust response to sintilimab in advanced distal cholangiocarcinoma with PD-L1 expression and DNA damage repair

Cholangiocarcinoma (CCA) is a highly heterogeneous tumor that occurs in the bile duct epithelium; adenosquamous carcinoma is a rare pathological subtype of CCA. The clinical treatment of patients with metastatic distal CCA poses significant challenges. We report a 53-year-old female diagnosed with a...

Full description

Bibliographic Details
Main Authors: Wenguang He, Congcong Song, Jiwei Ren, Xiao Ji, Xiuyan Wang, Lixia Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Pharmacology
Subjects:
cholangiocarcinoma
sintilimab
PD-L1
DNA damage repair
complete response
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1336699/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1336699/full

Similar Items