Segmental Duplications as a Complement Strategy to Short Tandem Repeats in the Prenatal Diagnosis of Down Syndrome

Segmental Duplications as a Complement Strategy to Short Tandem Repeats in the Prenatal Diagnosis of Down Syndrome

Background: Quantitative fluorescence-polymerase chain reaction (QF-PCR) is an inexpensive and accurate method for the prenatal diagnosis of aneuploidies that applies short tandem repeats (STRs) as a chromosome-specific marker. Despite its apparent advantages, QF-PCR is not applicable in all cases d...

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Bibliographic Details
Main Authors: Mohammad Reza Miri, Jamileh Saberzadeh, Abbas Behzad Behbahani, Mohammad Bagher Tabei, Mohsen Alipour, Majid Fardaei
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-05-01
Series:Iranian Journal of Medical Sciences
Subjects:
Multiplex polymerase chain reaction
Microsatellite repeats
Down syndrome
Segmental duplications
Online Access:http://ijms.sums.ac.ir/article_44976_2ac4b23ce124469fa3c464ebd4a20dc0.pdf

Internet

http://ijms.sums.ac.ir/article_44976_2ac4b23ce124469fa3c464ebd4a20dc0.pdf

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