Bcl-2 Inhibition Induces a Synergistic Effect in Combination with Doxorubicin in Chronic Lymphocytic Leukemia

Bcl-2 Inhibition Induces a Synergistic Effect in Combination with Doxorubicin in Chronic Lymphocytic Leukemia

Background: Chronic lymphocytic leukemia (CLL), a common neoplastic disease, is associated with the accumulation of B-lymphocytes in the hematopoietic organs. A main characteristic of CLL cells is the failure to undergo apoptosis, thus resulting in resistance to several chemotherapeutics. Doxorubici...

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Bibliographic Details
Main Authors: Mohammad Sadeghi, Koosha Sepasi, Amir Honarmand Alamdari, Ali Akbar Movasaghpour Akbari, Abbas Ali Hosseinpour Feizi, Sima Shahmohammadi Farid, Farhad Jadidi-Niaragh
Format: Article
Language:English
Published: Tabriz University of Medical Sciences 2022-12-01
Series:ImmunoAnalysis
Subjects:
cll
doxorubicin
bcl-2
leukemia
sirna
chemoresistance
Online Access:https://ia.tbzmed.ac.ir/PDF/ia-2-14.pdf

Internet

https://ia.tbzmed.ac.ir/PDF/ia-2-14.pdf

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