NR2F6 regulates stem cell hematopoiesis and myelopoiesis in mice

Nuclear receptors regulate hematopoietic stem cells (HSCs) and peripheral immune cells in mice and humans. The nuclear orphan receptor NR2F6 (EAR-2) has been shown to control murine hematopoiesis. Still, detailed analysis of the distinct stem cell, myeloid, and lymphoid progenitors in the bone marro...

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Bibliographic Details
Main Authors: Johannes Woelk, Hamsa Narasimhan, Christa Pfeifhofer-Obermair, Barbara U. Schraml, Natascha Hermann-Kleiter
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1404805/full