Steroid resistant CD8+ CD28null NKT-like pro-inflammatory cytotoxic cells in chronic obstructive pulmonary disease (COPD)

Corticosteroid resistance is a major barrier to effective treatment in chronic obstructive pulmonary disease (COPD), and failure to suppress systemic inflammation in these patients may result in increased co-morbidity. Although much of the research to date has focused on the role of macrophages and...

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Bibliographic Details
Main Authors: Greg Hodge, Sandra Hodge
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00617/full