Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles

Deriving a Boolean dynamics to reveal macrophage activation with in vitro temporal cytokine expression profiles

Abstract Background Macrophages show versatile functions in innate immunity, infectious diseases, and progression of cancers and cardiovascular diseases. These versatile functions of macrophages are conducted by different macrophage phenotypes classified as classically activated macrophages and alte...

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Bibliographic Details
Main Authors: Ricardo Ramirez, Allen Michael Herrera, Joshua Ramirez, Chunjiang Qian, David W. Melton, Paula K. Shireman, Yu-Fang Jin
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Bioinformatics
Subjects:
Macrophage polarization
Boolean networks
Cytokines
Inflammation
Online Access:https://doi.org/10.1186/s12859-019-3304-5

Internet

https://doi.org/10.1186/s12859-019-3304-5

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