HLA-DRB1 and –DQB1 Alleles, Haplotypes and Genotypes in Emirati Patients with Type 1 Diabetes Underscores the Benefits of Evaluating Understudied Populations

HLA-DRB1 and –DQB1 Alleles, Haplotypes and Genotypes in Emirati Patients with Type 1 Diabetes Underscores the Benefits of Evaluating Understudied Populations

Background: HLA class II (DR and DQ) alleles and antigens have historically shown strong genetic predisposition to type 1 diabetes (T1D). This study evaluated the association of DRB1 and DQB1 alleles, genotypes, and haplotypes with T1D in United Arab Emirates.Materials and Methods: Study subjects co...

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Bibliographic Details
Main Authors: Zain Al Yafei, Steven J. Mack, Marion Alvares, Bassam R. Ali, Bachar Afandi, Salem A. Beshyah, Charu Sharma, Wael Osman, Rajaa Mirghani, Amre Nasr, Sareea Al Remithi, Jamal Al Jubeh, Wasim Y. Almawi, Juma AlKaabi, Gehad ElGhazali
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Genetics
Subjects:
type 1 diabetes
HLA
haplotypes
Emiratis
ethnicity
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.841879/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.841879/full

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