HLA-DRB1 and –DQB1 Alleles, Haplotypes and Genotypes in Emirati Patients with Type 1 Diabetes Underscores the Benefits of Evaluating Understudied Populations
Background: HLA class II (DR and DQ) alleles and antigens have historically shown strong genetic predisposition to type 1 diabetes (T1D). This study evaluated the association of DRB1 and DQB1 alleles, genotypes, and haplotypes with T1D in United Arab Emirates.Materials and Methods: Study subjects co...
Main Authors: | Zain Al Yafei, Steven J. Mack, Marion Alvares, Bassam R. Ali, Bachar Afandi, Salem A. Beshyah, Charu Sharma, Wael Osman, Rajaa Mirghani, Amre Nasr, Sareea Al Remithi, Jamal Al Jubeh, Wasim Y. Almawi, Juma AlKaabi, Gehad ElGhazali |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-03-01
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Series: | Frontiers in Genetics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fgene.2022.841879/full |
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