Activation of Metabotropic Glutamate Receptor (mGlu<sub>2</sub>) and Muscarinic Receptors (M<sub>1</sub>, M<sub>4</sub>, and M<sub>5</sub>), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis

Activation of Metabotropic Glutamate Receptor (mGlu<sub>2</sub>) and Muscarinic Receptors (M<sub>1</sub>, M<sub>4</sub>, and M<sub>5</sub>), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis

The Morris water maze (MWM) is regarded as one of the most popular tests for detecting spatial memory in rodents. Long-term potentiation and cGMP synthesis seem to be among the crucial factors involved in this type of learning. Muscarinic (M<sub>1</sub>, M<sub>4</sub>, and M&...

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Bibliographic Details
Main Authors: Joanna M. Wierońska, Paulina Cieślik, Grzegorz Burnat, Leszek Kalinowski
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Biomolecules
Subjects:
Morris water maze
schizophrenia
spatial learning
muscarinic receptors
mGlu receptors
cGMP
Online Access:https://www.mdpi.com/2218-273X/13/7/1064

Internet

https://www.mdpi.com/2218-273X/13/7/1064

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