Impact of spill-in counts from off-target regions on [18F]Flortaucipir PET quantification

Impact of spill-in counts from off-target regions on [18F]Flortaucipir PET quantification

Background: [18F]Flortaucipir (FTP) PET quantification is usually hindered by spill-in counts from off-target binding (OFF) regions. The present work aims to provide an in-depth analysis of the impact of OFF in FTP PET quantification, as well as to identify optimal partial volume correction (PVC) st...

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Bibliographic Details
Main Authors: Francisco J. López-González, Alejandro Costoya-Sánchez, José Paredes-Pacheco, Alexis Moscoso, Jesús Silva-Rodríguez, Pablo Aguiar
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:NeuroImage
Subjects:
Tau PET
Monte Carlo
Off-target binding
PVE
SUVR
Online Access:http://www.sciencedirect.com/science/article/pii/S1053811922005134

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http://www.sciencedirect.com/science/article/pii/S1053811922005134

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