RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity

Plasmacytoid dendritic cells (pDCs) represent a unique immune cell type that responds to viral nucleic acids through the rapid production of type I interferons. Within the hematopoietic system, the transcription factor RUNX2 is exclusively expressed in pDCs and is required for their peripheral homeo...

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Bibliographic Details
Main Authors: Michaël Chopin, Simon P. Preston, Aaron T.L. Lun, Julie Tellier, Gordon K. Smyth, Marc Pellegrini, Gabrielle T. Belz, Lynn M. Corcoran, Jane E. Visvader, Li Wu, Stephen L. Nutt
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124716303552

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http://www.sciencedirect.com/science/article/pii/S2211124716303552

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