Single cell sequencing reveals that CD39 inhibition mediates changes to the tumor microenvironment

The molecular mechanisms underlying tumour heterogeneity in bladder cancer remain to be explored. Here, the authors perform single cell RNA sequencing and identify CD39 as a potential target for immunotherapy, which they validate in vivo.

Bibliographic Details
Main Authors: Lilong Liu, Yaxin Hou, Changqi Deng, Zhen Tao, Zhaohui Chen, Junyi Hu, Ke Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34495-z