The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres

The Effect of Polymer Blends on the In Vitro Release/Degradation and Pharmacokinetics of Moxidectin-Loaded PLGA Microspheres

To investigate the effect of polymer blends on the in vitro release/degradation and pharmacokinetics of moxidectin-loaded PLGA microspheres (MOX-MS), four formulations (F1, F2, F3 and F4) were prepared using the O/W emulsion solvent evaporation method by blending high (75/25, 75 kDa) and low (50/50,...

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Bibliographic Details
Main Authors: Hongjuan Zhang, Zhen Yang, Di Wu, Baocheng Hao, Yu Liu, Xuehong Wang, Wanxia Pu, Yunpeng Yi, Ruofeng Shang, Shengyi Wang
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:International Journal of Molecular Sciences
Subjects:
PLGA microspheres
moxidectin
polymer blends
in vitro release
pharmacokinetics
Online Access:https://www.mdpi.com/1422-0067/24/19/14729

Internet

https://www.mdpi.com/1422-0067/24/19/14729

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