Quantification of hypoxic regions distant from occlusions in cerebral penetrating arteriole trees.

The microvasculature plays a key role in oxygen transport in the mammalian brain. Despite the close coupling between cerebral vascular geometry and local oxygen demand, recent experiments have reported that microvascular occlusions can lead to unexpected distant tissue hypoxia and infarction. To bet...

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Bibliographic Details
Main Authors: Yidan Xue, Theodosia Georgakopoulou, Anne-Eva van der Wijk, Tamás I Józsa, Ed van Bavel, Stephen J Payne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1010166