Serotonergic modulation of the activity of GLP-1 producing neurons in the nucleus of the solitary tract in mouse

Objective: Glucagon-like peptide-1 (GLP-1) and 5-HT are potent regulators of food intake within the brain. GLP-1 is expressed by preproglucagon (PPG) neurons in the nucleus tractus solitarius (NTS). We have previously shown that PPG neurons innervate 5-HT neurons in the ventral brainstem. Here, we i...

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Bibliographic Details
Main Authors: Marie K. Holt, Ida J. Llewellyn-Smith, Frank Reimann, Fiona M. Gribble, Stefan Trapp
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Molecular Metabolism
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817303058