Intestinal injury and gut permeability in sickle cell disease
Abstract Background Due to recurrent hypoxia-reperfusion injury induced by vaso-occlusive crises (VOC), patients with sickle cell disease (SCD) may have intestinal injury and increased permeability. These may explain the qualitative and quantitative neutrophil abnormalities observed in these patient...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-05-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12967-019-1938-8 |