Anti-IL6 Autoantibodies in an Infant With CRP-Less Septic Shock

Anti-IL6 Autoantibodies in an Infant With CRP-Less Septic Shock

Background: Interleukin-6 (IL-6) is a pleiotropic cytokine with a multitude of pro-inflammatory effects. Serum C-reactive protein (CRP) is an acute phase protein induced mainly by IL-6 in response to inflammatory conditions, particularly infection. The biological functions of CRP include opsonisatio...

Full description

Bibliographic Details
Main Authors: Marketa Bloomfield, Zuzana Parackova, Tamara Cabelova, Iva Pospisilova, Pavel Kabicek, Hana Houstkova, Anna Sediva
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
interleukin 6
C-reactive protein
anti-IL6 autoantibodies
tocilizumab
siltuximab
sarilumab
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02629/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02629/full

Similar Items