Predicting DNA structure using a deep learning method

Abstract Understanding the mechanisms of protein-DNA binding is critical in comprehending gene regulation. Three-dimensional DNA structure, also described as DNA shape, plays a key role in these mechanisms. In this study, we present a deep learning-based method, Deep DNAshape, that fundamentally cha...

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Bibliographic Details
Main Authors: Jinsen Li, Tsu-Pei Chiu, Remo Rohs
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-45191-5