Novel highly sensitive chemiluminescence immunoassay for quantitation of durvalumab using a signal enhanced horseradish peroxidase-luminol-hydrogen peroxide reaction for detection system

Durvalumab (DUR) is a human monoclonal antibody used for the immunotherapy of lung cancer. It is a novel immune-checkpoint inhibitor, which blocks the programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) proteins and works to promote the normal immune responses that attack tumor cells. To...

Full description

Bibliographic Details
Main Authors: Ibrahim A. Darwish, Nourah Z. Alzoman, Nehal N.Y. Khalil, Hany W. Darwish
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:Talanta Open
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666831923000401