The paternal genome and the health of the assisted reproductive technology child

As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern. Does the integrity of the paternal genome impact on offspring health? In societal terms, as birth rates fall, and th...

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Bibliographic Details
Main Authors:	Sheena EM Lewis, Kishlay Kumar
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2015-01-01
Series:	Asian Journal of Andrology
Subjects:	gene regulation Musashi Musashi-1 Musashi-2 posttranscriptional control RNA binding proteins spermatogenesis splicing testis translation cell fate cell stress importin karyopherin nucleocytoplasmic transport spermatid spermatocyte artificial insemination biomarker fertility fertilization flow cytometry infertility nanotechnology oocyte activation Postacrosomal Sheath WWI Domain Binding Protein sperm SPTRX3 thioredoxin ubiquitin ATP binding cassette transporters albumin high-density lipoprotein lipid rafts membrane fluidity membrane microdomains membrane packing oxysterols reverse cholesterol transport sterol transporters egg heat shock protein A2 molecular chaperone sperm-egg interactions dehydrogenases oxidases peroxiredoxins reactive oxygen species spermatozoa thiols thioredoxins antigen-presenting cells autoimmunity dendritic cells epididymis macrophages peripheral tolerance sperm maturation genomics male infertility proteomics sperm chromatin sperm epigenetics sperm DNA damage paternal genome offspring
Online Access:	http://www.ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=4;spage=616;epage=622;aulast=Lewis

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2015;volume=17;issue=4;spage=616;epage=622;aulast=Lewis

The paternal genome and the health of the assisted reproductive technology child

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