Are 'endurance' alleles 'survival' alleles? Insights from the ACTN3 R577X polymorphism.

Are 'endurance' alleles 'survival' alleles? Insights from the ACTN3 R577X polymorphism.

Exercise phenotypes have played a key role for ensuring survival over human evolution. We speculated that some genetic variants that influence exercise phenotypes could be associated with exceptional survival (i.e. reaching ≥100 years of age). Owing to its effects on muscle structure/function, a pot...

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Bibliographic Details
Main Authors: Carmen Fiuza-Luces, Jonatan R Ruiz, Gabriel Rodríguez-Romo, Catalina Santiago, Félix Gómez-Gallego, Thomas Yvert, Amalia Cano-Nieto, Nuria Garatachea, María Morán, Alejandro Lucia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21407828/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21407828/?tool=EBI

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