Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells

Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells

Lan et al. report RNA structure ensembles across the entire SARSCoV-2 genome in infected human cells at single nucleotide resolution. They find alternative RNA conformations critical for promoting near-native frameshifting rates in ORF1ab.

Bibliographic Details
Main Authors: Tammy C. T. Lan, Matty F. Allan, Lauren E. Malsick, Jia Z. Woo, Chi Zhu, Fengrui Zhang, Stuti Khandwala, Sherry S. Y. Nyeo, Yu Sun, Junjie U. Guo, Mark Bathe, Anders Näär, Anthony Griffiths, Silvi Rouskin
Format: Article
Language:English
Published: Nature Portfolio 2022-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-28603-2

Internet

https://doi.org/10.1038/s41467-022-28603-2

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