Secondary structural ensembles of the SARS-CoV-2 RNA genome in infected cells
Lan et al. report RNA structure ensembles across the entire SARSCoV-2 genome in infected human cells at single nucleotide resolution. They find alternative RNA conformations critical for promoting near-native frameshifting rates in ORF1ab.
Bibliographic Details
| Main Authors: |
Tammy C. T. Lan,
Matty F. Allan,
Lauren E. Malsick,
Jia Z. Woo,
Chi Zhu,
Fengrui Zhang,
Stuti Khandwala,
Sherry S. Y. Nyeo,
Yu Sun,
Junjie U. Guo,
Mark Bathe,
Anders Näär,
Anthony Griffiths,
Silvi Rouskin |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-03-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-28603-2
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