Protective effect of yacon leaves extract (Smallanthus sonchifolius(Poepp.) H. Rob) through antifibrosis, anti-inflammatory, and antioxidant mechanisms toward diabetic nephropathy

Protective effect of yacon leaves extract (Smallanthus sonchifolius(Poepp.) H. Rob) through antifibrosis, anti-inflammatory, and antioxidant mechanisms toward diabetic nephropathy

Background and purpose: Diabetic nephropathy (DN) is a chronic kidney failure, which may lead to fatality. Mesangial cell proliferation, renal inflammation, stress oxidative, and fibrosis are involved in DN progression. Yacon leaves (Smallanthus sonchifolius (Poepp.) H. Rob.) contains large amounts...

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Bibliographic Details
Main Authors: Wahyu Widowati, Rita Tjokropranoto, Philips Onggowidjaja, Hanna Sari Widya Kusuma, Cahyaning Riski Wijayanti, Meganita Marthania, Afif Yati, Rizal Rizal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
diabetic nephropathy; mda; smads; tgf-β1; tnf-α; yacon leaves extract.
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=3;spage=336;epage=345;aulast=Widowati

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2023;volume=18;issue=3;spage=336;epage=345;aulast=Widowati

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