Dectin-2-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy

Dectin-2-Targeted Antifungal Liposomes Exhibit Enhanced Efficacy

ABSTRACT Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus cause life-threatening candidiasis, cryptococcosis, and aspergillosis, resulting in several hundred thousand deaths annually. The patients at the greatest risk of developing these life-threatening invasive fungal infection...

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Bibliographic Details
Main Authors: Suresh Ambati, Emma C. Ellis, Jianfeng Lin, Xiaorong Lin, Zachary A. Lewis, Richard B. Meagher
Format: Article
Language:English
Published: American Society for Microbiology 2019-10-01
Series:mSphere
Subjects:
liposomes
Dectin-2
exopolysaccharide matrix
mannan
amphotericin B
invasive fungal disease
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00715-19

Internet

https://journals.asm.org/doi/10.1128/mSphere.00715-19

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