ATP hydrolysis kinetics and thermodynamics as determinants of calcium oscillation in pancreatic β cells
Cellular ATP plays an important role in the calcium oscillation signal transduction pathway of pancreatic β cells. It triggers oscillation by binding the ATP-sensitive K^{+} channels (K_{ATP}), and maintains the oscillation by providing ATP hydrolysis free energy for the normal function of ion pumps...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Physical Society
2022-11-01
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| Series: | Physical Review Research |
| Online Access: | http://doi.org/10.1103/PhysRevResearch.4.043142 |