The role of leptin in regulation of the soluble amyloid precursor protein α (sAPPα) levels in lung cancer cell media

The role of leptin in regulation of the soluble amyloid precursor protein α (sAPPα) levels in lung cancer cell media

Abstract Previously, we found that the levels of soluble amyloid precursor protein α (sAPPα) are regulated, in part, by acetylcholinesterase (AChE) in human A549 (p53 wild-type) and H1299 (p53-null) NSCLC cell lines. In this study, we found regulation of sAPPα levels in the media by leptin, a widely...

Full description

Bibliographic Details
Main Authors: Ben Haddad, Jeneen Khalil, Hind Al Khashali, Ravel Ray, Stuti Goel, Ban Darweesh, Kai-ling Coleman, Caroline Wozniak, Robert Ranzenberger, Brooke Lopo, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-55717-y

Internet

https://doi.org/10.1038/s41598-024-55717-y

Similar Items