A neural crest cell isotropic-to-nematic phase transition in the developing mammalian gut

Chevalier et al. report that enteric neural crest cells transit during fetal development from an isotropic cell network to a square grid concomitantly with circular smooth muscle differentiation. They propose that smoothmuscle associated extracellular matrix drives this reorientation transition.

Bibliographic Details
Main Authors: Nicolas R. Chevalier, Yanis Ammouche, Anthony Gomis, Lucas Langlois, Thomas Guilbert, Pierre Bourdoncle, Sylvie Dufour
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02333-5