Rational design of aptamer switches with programmable pH response
Previous design strategies for pH sensitive aptamers were not readily tunable across pH ranges. Here the authors present a general method to convert aptamers into pH-responsive switches using two orthogonal motifs.
| Główni autorzy: | , , , |
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| Format: | Artykuł |
| Język: | English |
| Wydane: |
Nature Portfolio
2020-06-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-020-16808-2 |