Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

Pulmonary delivery of siRNA-loaded lipid-polymer hybrid nanoparticles: Effect of nanoparticle size

Nanomedicines based on nanoparticles rely both on the potency of the drug as well as the efficiency of the delivery system, for which particle size plays a crucial role. For the intracellular delivery of small interference RNA (siRNA), lipid-polymer nanoparticle (LPN) hybrid systems constitute a saf...

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Bibliographic Details
Main Authors: Abishek Wadhwa, Thomas R. Bobak, Lennart Bohrmann, Reka Geczy, Sathiya Sekar, Gowtham Sathyanarayanan, Jörg P. Kutter, Henrik Franzyk, Camilla Foged, Katayoun Saatchi, Urs O. Häfeli
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:OpenNano
Subjects:
Microfluidics
siRNA
Lipid-polymer hybrid nanoparticles (LPNs)
Size modulation
SPECT/CT
Pulmonary delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2352952023000592

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http://www.sciencedirect.com/science/article/pii/S2352952023000592

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