On-Chip Synthesis of Hyaluronic Acid-Based Nanoparticles for Selective Inhibition of CD44+ Human Mesenchymal Stem Cell Proliferation

On-Chip Synthesis of Hyaluronic Acid-Based Nanoparticles for Selective Inhibition of CD44+ Human Mesenchymal Stem Cell Proliferation

In this study, an innovative microfluidics-based method was developed for one-step synthesis of hyaluronic acid (HA)-based nanoparticles (NPs), by exploiting polyelectrolytic interactions between HA and chitosan (CS), in order to improve reliability, reproducibility and possible scale-up of the NPs...

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Bibliographic Details
Main Authors: Enrica Chiesa, Federica Riva, Rossella Dorati, Antonietta Greco, Stefania Ricci, Silvia Pisani, Maddalena Patrini, Tiziana Modena, Bice Conti, Ida Genta
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Pharmaceutics
Subjects:
hyaluronic acid-based nanocarriers
everolimus
chitosan
microfluidics
cd44 targeting
human mesenchymal stem cells
Online Access:https://www.mdpi.com/1999-4923/12/3/260

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https://www.mdpi.com/1999-4923/12/3/260

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