Recent Advances in the Application of Characterization Techniques for Studying Physical Stability of Amorphous Pharmaceutical Solids

Recent Advances in the Application of Characterization Techniques for Studying Physical Stability of Amorphous Pharmaceutical Solids

The amorphous form of a drug usually exhibits higher solubility, faster dissolution rate, and improved oral bioavailability in comparison to its crystalline forms. However, the amorphous forms are thermodynamically unstable and tend to transform into a more stable crystalline form, thus losing their...

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Bibliographic Details
Main Authors: Yanan Wang, Yong Wang, Jin Cheng, Haibiao Chen, Jia Xu, Ziying Liu, Qin Shi, Chen Zhang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Crystals
Subjects:
amorphous drug
characterization methods
crystallization
physical stability
molecular mobility
Online Access:https://www.mdpi.com/2073-4352/11/12/1440

Internet

https://www.mdpi.com/2073-4352/11/12/1440

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