Transendothelial migration enables subsequent transmigration of neutrophils through underlying pericytes.

During acute inflammation, neutrophil recruitment into extravascular tissue requires neutrophil tethering and rolling on cytokine-activated endothelial cells (ECs), tight adhesion, crawling towards EC junctions and transendothelial migration (TEM). Following TEM, neutrophils must still traverse the...

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Bibliographic Details
Main Authors: Chantal E Ayres-Sander, Holly Lauridsen, Cheryl L Maier, Parid Sava, Jordan S Pober, Anjelica L Gonzalez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3608600?pdf=render