5-HT7 receptor activation promotes an increase in TrkB receptor expression and phosphorylation

5-HT7 receptor activation promotes an increase in TrkB receptor expression and phosphorylation

The serotonin (5-HT) type 7 receptor is expressed throughout the CNS including cortical neurons. We have previously demonstrated that the application of 5-HT7 receptor agonists to primary hippocampal neurons and SH-SY5Y cells increases platelet-derived growth factor (PDGF) receptor expression and pr...

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Bibliographic Details
Main Authors: Anshula eSamarajeewa, Lolita eGoldemann, Maryam S Vasefi, Nawaz eAhmed, Nyasha eGondora, Chandni eKhanderia, John G. Mielke, Michael A Beazely
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Phosphorylation
protein expression
TrkB
transactivation
T1
5-HT7
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00391/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00391/full

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