A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy

A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy

Abstract Background JC polyomavirus (JCV) is the causative agent of progressive multifocal leukoencephalopathy (PML), a demyelinating disease of the central nervous system in immunosuppressed patients. PML usually has a poor prognosis. Detection and quantification of the JCV genome in cerebrospinal...

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Bibliographic Details
Main Authors: Hitomi Kinoshita, Kazuo Nakamichi, Chang-Kweng Lim, Mutsuyo Takayama-Ito, Lixin Wang, Itoe Iizuka, Ichiro Kurane, Masayuki Saijo
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Virology Journal
Subjects:
LAMP
PML
JC polyomavirus
Detection
Quantification
Online Access:http://link.springer.com/article/10.1186/s12985-018-1046-z

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http://link.springer.com/article/10.1186/s12985-018-1046-z

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