Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease

Multimodal PET-fMRI imaging of Alzheimer’s disease patients and healthy controls suggests that microglia activation in the posterior cingulate cortex is associated with increased brain activity in Alzheimer’s disease, and independent of amyloid accumulation.

Bibliographic Details
Main Authors: Nádia Canário, Lília Jorge, Ricardo Martins, Isabel Santana, Miguel Castelo-Branco
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03761-7