Dual PET-fMRI reveals a link between neuroinflammation, amyloid binding and compensatory task-related brain activity in Alzheimer’s disease
Multimodal PET-fMRI imaging of Alzheimer’s disease patients and healthy controls suggests that microglia activation in the posterior cingulate cortex is associated with increased brain activity in Alzheimer’s disease, and independent of amyloid accumulation.
Main Authors: | Nádia Canário, Lília Jorge, Ricardo Martins, Isabel Santana, Miguel Castelo-Branco |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-08-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03761-7 |
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